Expiration date: 07/2009. 2 pack. Zicam Cold Remedy is an over-the-counter homeopathic medicine that actually reduces the duration and severity of the common cold when taken at the first sign of cold symptoms. Zicam Cold Remedy acts at the source - the nasal cavity. The nasal cavity is the main site of the cold virus' entry into the body. A clinical study has shown that Zicam Nasal Cold Remedy gets rid of the cold three times faster reducing the duration by an average of 75% when taken at the onset of symptoms.